Medical technology and devices

Customized plasma technologies for targeted cell adhesion

Selectively functionalized surface for the formation of “hanging drops” for 3D cell models.
© Fraunhofer IST, Falko Oldenburg
Selectively functionalized surface for the formation of “hanging drops” for 3D cell models.

Achieving better biocompatibility through targeted approaches

As modern therapies advance, the need for functional surfaces in medical technology is growing. In particular, the targeted control of cell adhesion is crucial for the success of implants and medical devices. While adhesive properties promote integration into the body, anti-adhesive surfaces prevent the formation of biofilms as well as contamination by pathogenic organisms, thereby reducing the risk of infection. However, many materials exhibit low affinity for biological cells. At the same time, biofilm formation and inadequate surface properties pose major challenges. Solutions are therefore needed that specifically improve biocompatibility and reliably ensure functionality.

Precise and efficient surface optimization

We use plasma processes to specifically modify surface chemistry. This allows us to precisely adjust surface energy and chemical composition. Functional groups enable both the control of cell adhesion and the binding of biomolecules. We place a special focus on developing customized plasma sources that are optimally tailored to your materials. This is complemented by comprehensive surface analysis, which we use to precisely characterize coating composition and stability as well as wetting behavior and functionality.

Greater performance and flexibility for your products

By using dry plasma processes, you can eliminate the need for complex wet chemical processes. This simplifies handling, reduces costs, and lowers resource consumption. At the same time, our technologies enable the selective modification of even complex geometries as well as targeted internal coating. This allows you to precisely tailor specific functional areas of your medical devices. Our custom-developed plasma sources offer you the flexibility to efficiently bring innovative and high-performance products to market.

Ausgewählte Referenzprojekte

 

Reference project

StrepTag-mediated chromatography

on 3D-printed matrices

 

Reference project

Adapted surfaces for the control of cell adhesion

Aus der Forschung

 

Aus der Forschung

Verbesserung der inhalativen Therapie durch Antihaftoberflächen

We offer solutions for your applications

 

Industry solutions

Medical and pharmaceutical process engineering

Our focus and expertise

 

Technology

Atmospheric pressure plasma processes

 

Expertise

Pretreatment and functionalization